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While erasing facial wrinkles remains the best known use for Botox and accounted for roughly half of its global sales of $2.78 billion in 2016, Allergan has continually tested the drug for a wide variety of medical conditions.

Among the already approved medical uses for Botox are chronic migraine, overactive bladder, severe underarm sweating, eyelid spasms and limb spasticity.

The drug, given through a series of facial injections, just missed achieving a statistically significant improvement compared with placebo on the lower of two tested doses as measured by change from baseline at week 6 in the Montgomery-Asberg Depression Rating Scale (MADRS), the company said.

Read the full article at: mobile.reuters.com